INT237328

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.02
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (PARPBP) nucleus (PARPBP) DNA binding (PARPBP)
cytoplasm (PARPBP)
Anatomy Link Frequency
astrocytes 1
knee 1
PARPBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 41 94.16 High High
Morphine 53 88.36 High High
Pain score 4 79.32 Quite High
cytokine 19 78.24 Quite High
IPN 1 67.16 Quite High
Neurotransmitter 1 23.28 Low Low
Inflammation 12 5.00 Very Low Very Low Very Low
Opioid 6 5.00 Very Low Very Low Very Low
opiate 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 10 95.84 Very High Very High Very High
Pain 46 94.16 High High
Reprotox - General 2 1 89.20 High High
Disease 34 87.48 High High
Fatigue 5 86.36 High High
Contracture 36 74.96 Quite High
Inflammatory Pain 1 67.16 Quite High
Complex Regional Pain Syndromes 5 50.00 Quite Low
Blister 11 48.88 Quite Low
Frailty 5 34.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We showed upregulation of AROM activity in astrocytes in vitro[6] and Amini et al. [7] demonstrated an increase of 5-alpha reductase expression in vivo.
Positive_regulation (upregulation) of AROM in astrocytes
1) Confidence 0.14 Published 2010 Journal Mol Pain Section Body Doc Link PMC2978140 Disease Relevance 0.23 Pain Relevance 0.51
for both), with no significant increase in AROM at T2 compared to T1 (P = .353).
Neg (no) Positive_regulation (increase) of AROM
2) Confidence 0.12 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2441694 Disease Relevance 0.86 Pain Relevance 0.54
Increasing the AROM following this operation is imperative to the patient's complete recovery [6,9,10].
Positive_regulation (Increasing) of AROM
3) Confidence 0.03 Published 2008 Journal Cases J Section Body Doc Link PMC2615769 Disease Relevance 0.45 Pain Relevance 0
It was worn for six to eight hours per night for eight weeks, and the patient regained full AROM in knee extension, (0°).
Positive_regulation (regained) of AROM in knee
4) Confidence 0.03 Published 2008 Journal Cases J Section Body Doc Link PMC2615769 Disease Relevance 0.48 Pain Relevance 0.09

General Comments

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