INT237352

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (QDPR) mitochondrion (QDPR) small molecule metabolic process (QDPR)
oxidoreductase activity (QDPR) cellular nitrogen compound metabolic process (QDPR) cellular amino acid metabolic process (QDPR)
Anatomy Link Frequency
skeletal muscle 1
QDPR (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
Sciatic nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Structural Myopathies 17 50.00 Quite Low
Muscle Weakness 4 12.64 Low Low
Frailty 2 11.04 Low Low
Cytomegalovirus Infection 13 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Muscle Disease 5 5.00 Very Low Very Low Very Low
Charcot Marie Tooth Disease 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results indicate that when highly overexpressed in skeletal muscle, myotubularin alters membrane homeostasis leading to the formation of packed membrane assemblies close to the sarcolemma and of vacuoles that are positive for dystrophin, caveolin-3 and DHPR?
Positive_regulation (positive) of DHPR in skeletal muscle
1) Confidence 0.20 Published 2008 Journal Human Molecular Genetics Section Body Doc Link PMC2441725 Disease Relevance 0 Pain Relevance 0

General Comments

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