INT237353

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (MTM1) cytoplasm (MTM1)
Anatomy Link Frequency
muscle 1
MTM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 88.04 High High
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
Sciatic nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 88.04 High High
Muscle Weakness 4 84.32 Quite High
Disease 5 79.12 Quite High
Cytomegalovirus Infection 13 75.20 Quite High
Congenital Structural Myopathies 17 50.00 Quite Low
Muscle Disease 5 5.00 Very Low Very Low Very Low
Charcot Marie Tooth Disease 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Altogether, our results demonstrate that a single intramuscular injection of a rAAV vector carrying a Mtm1 cDNA is sufficient to ameliorate the pathology of an already affected XLMTM muscle.


Regulation (affected) of XLMTM in muscle
1) Confidence 0.04 Published 2008 Journal Human Molecular Genetics Section Body Doc Link PMC2441725 Disease Relevance 0.39 Pain Relevance 0.04

General Comments

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