INT237379

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.71
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ebi3, Il27) extracellular region (Ebi3, Il27)
Ebi3 (Mus musculus)
Il27 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 2 98.16 Very High Very High Very High
agonist 66 96.24 Very High Very High Very High
Inflammation 27 95.68 Very High Very High Very High
rheumatoid arthritis 2 83.44 Quite High
cytokine 90 82.88 Quite High
Multiple sclerosis 32 80.88 Quite High
Central nervous system 21 32.08 Quite Low
antagonist 5 7.68 Low Low
chemokine 12 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Epstein-barr Virus 3 100.00 Very High Very High Very High
Experimental Arthritis 2 98.16 Very High Very High Very High
Disease 23 96.24 Very High Very High Very High
INFLAMMATION 28 95.68 Very High Very High Very High
Autoimmune Disease 2 92.64 High High
Infection 76 91.76 High High
Multiple Sclerosis 62 86.96 High High
Rheumatoid Arthritis 2 83.44 Quite High
Arthritis 2 79.44 Quite High
Inflammatory Bowel Disease 4 47.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
of p28 in association with EBV-induced molecule 3 (EBI3).
EBI3 Binding (association) of p28 associated with epstein-barr virus
1) Confidence 0.05 Published 2008 Journal PPAR Research Section Body Doc Link PMC2441778 Disease Relevance 0.44 Pain Relevance 0.28
In addition to associating with p28 in IL-27, the EBi3 subunit can also couple with p35 to facilitate secretion of the latter [48].
EBi3 subunit Binding (associating) of p28
2) Confidence 0.04 Published 2011 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2963117 Disease Relevance 0.74 Pain Relevance 0.28
The p28, protein was only found to be efficiently secreted when coupled with EBI3.
EBI3 Binding (coupled) of p28
3) Confidence 0.04 Published 2011 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2963117 Disease Relevance 0.53 Pain Relevance 0.26

General Comments

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