INT237404

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Adam10) nucleocytoplasmic transport (Adam10) Golgi apparatus (Adam10)
nucleus (Adam10) cytoplasm (Adam10)
Adam10 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 1 88.40 High High
Inflammation 46 58.84 Quite High
cINOD 45 57.44 Quite High
COX-2 inhibitor 1 45.60 Quite Low
cytokine 11 34.96 Quite Low
glial activation 2 30.52 Quite Low
Hippocampus 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 17 96.00 Very High Very High Very High
Amyloid Plaque 11 94.60 High High
Cognitive Disorder 12 88.96 High High
Disease 52 88.88 High High
Necrosis 2 67.76 Quite High
Cancer 2 67.40 Quite High
INFLAMMATION 55 58.84 Quite High
Pathologic Processes 1 28.16 Quite Low
Alzheimer's Dementia 7 5.00 Very Low Very Low Very Low
Brain Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-secretase of APP, revealed activation of ADAM10 as a promising therapeutic target, and supported the hypothesis that a decrease in ?
Regulation (-) of Positive_regulation (activation) of ADAM10
1) Confidence 0.30 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2442055 Disease Relevance 0.83 Pain Relevance 0.16

General Comments

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