INT237411

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Erbb4) mitochondrion (Erbb4) plasma membrane (Erbb4)
nucleus (Erbb4) kinase activity (Erbb4) cytoplasm (Erbb4)
Anatomy Link Frequency
Notch 2
Erbb4 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 45 99.20 Very High Very High Very High
antagonist 3 55.36 Quite High
cOX1 1 49.44 Quite Low
Inflammation 46 6.04 Low Low
cytokine 11 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
glial activation 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 17 76.16 Quite High
INFLAMMATION 55 50.00 Quite Low
Cognitive Disorder 12 44.96 Quite Low
Disease 52 42.96 Quite Low
Amyloid Plaque 11 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 7 5.00 Very Low Very Low Very Low
Brain Injury 6 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Dementia 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nonetheless, since NSAIDs, even at higher concentrations did not inhibit cleavage of Notch and ErbB4 or alter AICD formation, this class of inhibitors might be valuable compounds to selectively decrease A?
Negative_regulation (inhibit) of Localization (cleavage) of ErbB4 in Notch associated with cinod
1) Confidence 0.25 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2442055 Disease Relevance 0.08 Pain Relevance 0.64

General Comments

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