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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.20
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Bace1, Bace1) Golgi apparatus (Bace1, Bace1) endoplasmic reticulum (Bace1, Bace1)
enzyme binding (Bace1, Bace1) peptidase activity (Bace1, Bace1) cell differentiation (Hif1a)
Hif1a (Mus musculus)
Bace1 (Mus musculus)
Bace1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 4 83.72 Quite High
Inflammation 46 79.28 Quite High
Inflammatory response 2 76.44 Quite High
Eae 1 44.84 Quite Low
cytokine 11 41.08 Quite Low
antagonist 3 33.68 Quite Low
glial activation 2 17.96 Low Low
cINOD 45 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Injury 6 95.36 Very High Very High Very High
Hypoxia 1 95.36 Very High Very High Very High
INFLAMMATION 55 79.28 Quite High
Disease 52 78.76 Quite High
Injury 5 77.88 Quite High
Disease Progression 1 75.68 Quite High
Dementia 3 54.88 Quite High
Amyloid Plaque 11 24.16 Low Low
Targeted Disruption 17 20.92 Low Low
Cognitive Disorder 12 9.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This action is thought to be mediated by the binding of HIF-1 to the promoter region of BACE1 mRNA resulting in increased levels of BACE1 protein in the tissue [41].
HIF-1 Binding (binding) of BACE1 Positive_regulation (levels) of BACE1 protein
1) Confidence 0.06 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2442055 Disease Relevance 1.20 Pain Relevance 0.15

General Comments

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