INT237569

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.07
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl1) extracellular region (Cxcl1)
Cxcl1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 26 94.36 High High
isoflurane 6 69.00 Quite High
ketamine 2 66.76 Quite High
Inflammation 27 50.00 Quite Low
anesthesia 3 47.92 Quite Low
addiction 18 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Neuronal excitability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Exsanguination 2 71.76 Quite High
Pneumonia 14 50.00 Quite Low
Body Weight 2 5.28 Low Low
INFLAMMATION 24 5.00 Very Low Very Low Very Low
Adult Respiratory Distress Syndrome 14 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low
Lung Injury 7 5.00 Very Low Very Low Very Low
Hyperoxia 2 5.00 Very Low Very Low Very Low
Reperfusion Injury 2 5.00 Very Low Very Low Very Low
Atypical Pneumonia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Multiplex bead immunoassay (Lincoplex) was performed according to the manufacturer's protocol on the Luminex 100 platform to measure concentrations of KC/CXCL1, MCP-1/CCL2, MIP-1?
Negative_regulation (measure) of CXCL1 Binding (concentrations) of
1) Confidence 0.41 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC3002319 Disease Relevance 0.07 Pain Relevance 0.19
The fact that the IC50 for ATP inhibition of macroscopic currents through 4M channels was also increased indicates that the K185E mutation also reduces the affinity of ATP binding to the long closed states (KC).
Negative_regulation (reduces) of KC Binding (binding) of
2) Confidence 0.05 Published 2008 Journal The Journal of General Physiology Section Body Doc Link PMC2442177 Disease Relevance 0 Pain Relevance 0

General Comments

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