INT237634

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Nfasc) plasma membrane (Nfasc)
Nfasc (Mus musculus)
Ank3 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 49 100.00 Very High Very High Very High
sodium channel 39 84.20 Quite High
Spinal cord 9 64.08 Quite High
potassium channel 2 56.56 Quite High
Nav1.6 5 51.20 Quite High
unmyelinated 1 21.48 Low Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Nav1.2 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 10 88.80 High High
Adhesions 16 76.40 Quite High
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low
Lifespan 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests that the transient expression of AnkyrinG at the paranodes during the postnatal development of myelinated CNS fibers does not depend on either Nfasc155 or its axonal partners Caspr and Contactin because in the absence of Nfasc155, there was no amelioration of the mislocalization of Caspr (Fig. 3 B).
Nfasc155 Neg (not) Positive_regulation (depend) of Gene_expression (expression) of AnkyrinG associated with central nervous system
1) Confidence 0.02 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2442198 Disease Relevance 0.23 Pain Relevance 0.32

General Comments

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