INT237652

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.17
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Sfn) nucleus (Sfn) cytoplasm (Sfn)
Sfn (Mus musculus)
Pain Link Frequency Relevance Heat
peripheral neuropathy 3 95.56 Very High Very High Very High
Pain 57 75.44 Quite High
spinal stenosis 1 65.36 Quite High
Hypoesthesia 4 60.76 Quite High
Neuropathic pain 18 50.32 Quite High
unmyelinated 2 48.80 Quite Low
c fibre 8 47.76 Quite Low
qutenza 1 45.76 Quite Low
nociceptor 1 42.16 Quite Low
Quantitative sensory testing 36 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 178 100.00 Very High Very High Very High
Syndrome 7 95.68 Very High Very High Very High
Non-diabetic Peripheral Neuropathy 8 95.56 Very High Very High Very High
Pain 64 75.44 Quite High
Spinal Cord Diseases 2 65.84 Quite High
Spinal Stenosis 1 65.36 Quite High
Cv Unclassified Under Development 3 64.68 Quite High
Hypesthesia 4 60.76 Quite High
Diabetic Nephropathy 5 45.04 Quite Low
Nociception 1 35.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The sequence for MmeI was included in GEX DpnII adapter 1.
Positive_regulation (sequence) of MmeI
1) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2993968 Disease Relevance 0 Pain Relevance 0
Overall, these studies have contributed to increase the awareness on SFN among neurologists and others specialists, such as diabetologists, but did not lead to a definition of the syndrome.
Positive_regulation (increase) of SFN associated with syndrome and neuropathic pain
2) Confidence 0.38 Published 2008 Journal Brain Section Body Doc Link PMC2442424 Disease Relevance 1.17 Pain Relevance 0.27
Because our study showed that knockdown of endogenous CRIF1 enhanced SFN-induced NRF2 total and nuclear expression (Fig. 3, C and D), we determined whether the induced nuclear NRF2 binds to an ARE-containing DNA sequence.
Positive_regulation (enhanced) of SFN-induced
3) Confidence 0.21 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2898415 Disease Relevance 0 Pain Relevance 0

General Comments

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