INT237655

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 3.62
Pain Relevance 2.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Sfn) nucleus (Sfn) cytoplasm (Sfn)
Anatomy Link Frequency
skin 2
Sfn (Mus musculus)
Pain Link Frequency Relevance Heat
Quantitative sensory testing 144 99.72 Very High Very High Very High
unmyelinated 8 97.60 Very High Very High Very High
Hyperalgesia 32 95.88 Very High Very High Very High
Neuropathic pain 72 90.64 High High
allodynia 72 90.20 High High
Pain 228 86.68 High High
c fibre 32 80.36 Quite High
Spontaneous pain 36 72.76 Quite High
Hypoesthesia 16 44.00 Quite Low
spinal stenosis 4 35.04 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 712 100.00 Very High Very High Very High
Autonomic Nervous System Disease 4 99.04 Very High Very High Very High
Hyperalgesia 32 95.88 Very High Very High Very High
Nociception 4 93.84 High High
Pain 256 86.68 High High
Non-diabetic Peripheral Neuropathy 32 83.20 Quite High
Increased Venous Pressure Under Development 40 80.80 Quite High
Diabetic Nephropathy 20 76.08 Quite High
Syndrome 28 63.84 Quite High
Spinal Cord Diseases 8 62.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, we found that SFN is associated with clinical signs of dysautonomia, which were most commonly limited to sweating and peripheral vascular impairment.
SFN Binding (associated) of associated with autonomic nervous system disease and neuropathic pain
1) Confidence 0.42 Published 2008 Journal Brain Section Body Doc Link PMC2442424 Disease Relevance 1.41 Pain Relevance 0.89
We observed a significant inverse correlation between IENF density and thermal thresholds at the distal leg, namely at the site commonly used to diagnose SFN with skin biopsy.
SFN Binding (diagnose) of in skin associated with neuropathic pain
2) Confidence 0.32 Published 2008 Journal Brain Section Body Doc Link PMC2442424 Disease Relevance 0.23 Pain Relevance 0.40
fibres, small fibre neuropathy (SFN) has been recognized as a distinct nosologic entity.
SFN Binding (recognized) of associated with neuropathic pain
3) Confidence 0.31 Published 2008 Journal Brain Section Body Doc Link PMC2442424 Disease Relevance 1.00 Pain Relevance 0.29
Diagnostic yield of skin biopsy, QST and clinical findings in SFN
SFN Binding (findings) of in skin associated with quantitative sensory testing and neuropathic pain
4) Confidence 0.28 Published 2008 Journal Brain Section Body Doc Link PMC2442424 Disease Relevance 0.98 Pain Relevance 0.97

General Comments

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