INT23767

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Context Info
Confidence 0.67
First Reported 1983
Last Reported 1988
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 1.96
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SERPINA7) aging (SERPINA7) extracellular region (SERPINA7)
Anatomy Link Frequency
thyroid 3
SERPINA7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 3 99.88 Very High Very High Very High
methadone 10 99.84 Very High Very High Very High
withdrawal 2 80.24 Quite High
Pain 1 75.56 Quite High
Disease Link Frequency Relevance Heat
Thyroid Neoplasm 3 99.96 Very High Very High Very High
Pancreatitis 3 99.88 Very High Very High Very High
Papillary Adenocarcinoma 3 99.60 Very High Very High Very High
Hyperamylasemia 6 99.34 Very High Very High Very High
Disorder Of Lipid Metabolism 1 90.04 High High
Hypoalbuminemia 1 84.36 Quite High
Congenital Anomalies 4 81.48 Quite High
Pain 1 75.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Macroamylasemia associated with thyroid cancer, elevated serum thyroxine-binding globulin (TBG), chronic pancreatitis and gastrointestinal polyposis.
Positive_regulation (elevated) of TBG in thyroid associated with thyroid neoplasm, hyperamylasemia and chronic pancreatitis
1) Confidence 0.67 Published 1986 Journal Gastroenterol. Jpn. Section Title Doc Link 2429888 Disease Relevance 0.49 Pain Relevance 0.10
Macroamylasemia associated with thyroid cancer, elevated serum thyroxine-binding globulin (TBG), chronic pancreatitis and gastrointestinal polyposis.
Positive_regulation (elevated) of serum thyroxine-binding globulin in thyroid associated with thyroid neoplasm, hyperamylasemia and chronic pancreatitis
2) Confidence 0.46 Published 1986 Journal Gastroenterol. Jpn. Section Title Doc Link 2429888 Disease Relevance 0.49 Pain Relevance 0.10
A case of macroamylasemia in a 78 year-old female, associated with papillary adenocarcinoma of the thyroid and elevated serum thyroxine-binding globulin was described.
Positive_regulation (elevated) of serum thyroxine-binding globulin in thyroid associated with papillary adenocarcinoma and hyperamylasemia
3) Confidence 0.46 Published 1986 Journal Gastroenterol. Jpn. Section Abstract Doc Link 2429888 Disease Relevance 0.42 Pain Relevance 0.07
A minor increase in serum thyroxin was recorded, probably because of the increase in thyroxin binding globulin.
Positive_regulation (increase) of thyroxin binding globulin
4) Confidence 0.23 Published 1983 Journal Sem Hop Section Abstract Doc Link 6301031 Disease Relevance 0.25 Pain Relevance 0.08
There was a corresponding decrease in the T3 uptake (T3U) test, but the free thyroxin index (FTI) failed to correct for the increased TBG concentration in 15.9% of the patients.
Positive_regulation (increased) of TBG
5) Confidence 0.22 Published 1988 Journal Clin. Chem. Section Abstract Doc Link 3141082 Disease Relevance 0.16 Pain Relevance 0.42
We conclude that prolonged therapy with methadone causes increases in TBG, T3, and T4 in serum.
Positive_regulation (increases) of TBG associated with methadone
6) Confidence 0.19 Published 1988 Journal Clin. Chem. Section Abstract Doc Link 3141082 Disease Relevance 0.14 Pain Relevance 0.44

General Comments

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