INT237700

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.08
Pain Relevance 2.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6) nucleus (IRF6) DNA binding (IRF6)
cytoplasm (IRF6)
Anatomy Link Frequency
neutrophils 4
IRF6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 412 100.00 Very High Very High Very High
narcan 20 99.22 Very High Very High Very High
Inflammation 48 93.20 High High
Opioid 12 79.12 Quite High
opioid receptor 84 69.60 Quite High
antagonist 4 62.04 Quite High
ischemia 1 56.52 Quite High
Arthritis 6 51.84 Quite High
Codeine 10 5.00 Very Low Very Low Very Low
opiate 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malaria 1 96.68 Very High Very High Very High
INFLAMMATION 57 93.20 High High
Disease 4 92.16 High High
Renal Disease 1 86.32 High High
Sepsis 94 84.96 Quite High
Reperfusion Injury 1 57.28 Quite High
Cv Unclassified Under Development 1 56.52 Quite High
Arthritis 6 51.84 Quite High
Apoptosis 3 20.72 Low Low
Infection 38 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, naloxone was able to significantly inhibit the effect of exogenous morphine on neutrophils treated with LPS compared to LPS and morphine incubation alone (49±5 ng/106 neutrophils ±SD, n?
Regulation (effect) of Negative_regulation (treated) of LPS in neutrophils associated with narcan and morphine
1) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2808358 Disease Relevance 0.08 Pain Relevance 1.14
Finally, naloxone was able to significantly inhibit the effect of exogenous morphine on neutrophils treated with LPS compared to LPS and morphine incubation alone (49±5 ng/106 neutrophils ±SD, n?
Regulation (effect) of Negative_regulation (treated) of LPS in neutrophils associated with narcan and morphine
2) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2808358 Disease Relevance 0.08 Pain Relevance 1.15
Taken together, our data indicate that inhibition of JNK signal is the most involved in the inhibitory effect of melittin and bee venom on the LPS and SNP-induced activation of NF-?
Regulation (involved) of Negative_regulation (effect) of LPS
3) Confidence 0.03 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2442592 Disease Relevance 0.91 Pain Relevance 0.29

General Comments

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