INT237738

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.98
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Jak3) transcription factor binding (Jak3) cytoplasm (Jak3)
Jak3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 8 99.96 Very High Very High Very High
chemokine 6 78.16 Quite High
Inflammatory response 14 74.84 Quite High
Inflammatory marker 2 66.16 Quite High
Inflammation 56 61.84 Quite High
ischemia 2 24.56 Low Low
ketamine 4 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
GABA receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 116 93.92 High High
Ganglion Cysts 6 85.36 High High
INFLAMMATION 72 74.48 Quite High
Epiretinal Membrane 2 74.16 Quite High
Diabetic Retinopathy 64 62.12 Quite High
Insulin Resistance 2 51.84 Quite High
Retina Disease 2 25.20 Quite Low
Neurodegenerative Disease 4 13.08 Low Low
Adhesions 10 11.04 Low Low
Apoptosis 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
JAK3 (janus kinase 3) expression requires cytokine signaling and inhibition of JAK3 prevents STAT3 activation [36].
Positive_regulation (requires) of Gene_expression (expression) of JAK3 associated with cytokine
1) Confidence 0.32 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2442612 Disease Relevance 0.99 Pain Relevance 0.24
JAK3 (janus kinase 3) expression requires cytokine signaling and inhibition of JAK3 prevents STAT3 activation [36].
Positive_regulation (requires) of Gene_expression (expression) of janus kinase 3 associated with cytokine
2) Confidence 0.32 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2442612 Disease Relevance 0.99 Pain Relevance 0.24

General Comments

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