INT237768

Context Info Confidence 0.67 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.46 Pain Relevance 0.10

nucleus (Tbx21) DNA binding (Tbx21)

Tbx21 (Mus musculus)

Pain Link Frequency Relevance Heat Spinal cord 5 72.76 chemokine 12 66.44 Central nervous system 29 66.04 cytokine 7 50.00 Multiple sclerosis 10 5.00 Inflammation 8 5.00 Demyelination 2 5.00 Neuritis 1 5.00 Arthritis 1 5.00 medulla 1 5.00

Disease Link Frequency Relevance Heat Multiple Sclerosis 46 81.40 Central Nervous System Disease 25 66.04 Disease 17 64.00 Spinal Cord Diseases 1 60.72 Syndrome 1 50.64 Paralysis 2 43.84 INFLAMMATION 8 5.00 Demyelinating Disease 7 5.00 Immunization 4 5.00 Autoimmune Disease 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Cells cultured with IL-12p70 up-regulated the Th1-associated transcription factor, T-bet, and secreted IFN-?

Transcription (transcription) of T-bet

1) Confidence 0.67 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442630 Disease Relevance 0.46 Pain Relevance 0.10

General Comments

This test has worked.