INT237769

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

thd (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 7 72.48 Quite High
Central nervous system 29 63.36 Quite High
chemokine 12 50.00 Quite Low
Multiple sclerosis 10 47.64 Quite Low
Inflammation 8 34.24 Quite Low
Spinal cord 5 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 46 86.04 High High
Hypersensitivity 1 68.28 Quite High
Central Nervous System Disease 25 63.36 Quite High
Disease 17 54.84 Quite High
Autoimmune Disease 3 46.52 Quite Low
Immunization 4 38.68 Quite Low
INFLAMMATION 8 34.24 Quite Low
Syndrome 1 33.52 Quite Low
Spinal Cord Diseases 1 13.44 Low Low
Demyelinating Disease 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, these observations invite an alternative interpretation of the mechanism of action of IL-12p40 in neuroinflammation; namely, that its role is in the production of IL-23 and reinforcement of the Th17 effector cell population, rather than (or in addition to) the production of IL-12p70 and promotion of Th1 differentiation.
Regulation (role) of Gene_expression (production) of Th17
1) Confidence 0.00 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442630 Disease Relevance 0.46 Pain Relevance 0.10

General Comments

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