INT237808

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Stim1, Trpv1) plasma membrane (Stim1, Trpv1) endoplasmic reticulum (Stim1)
transmembrane transport (Trpv1) lipid metabolic process (Trpv1) cytoplasm (Stim1)
Anatomy Link Frequency
T cells 1
Stim1 (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
TRP channel 1 99.16 Very High Very High Very High
agonist 21 66.16 Quite High
cva 6 40.40 Quite Low
imagery 7 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coagulation Disorder 1 72.08 Quite High
Thrombosis 28 59.84 Quite High
Brain Hemorrhage 16 57.60 Quite High
Cv General 4 Under Development 6 56.56 Quite High
Death 4 50.04 Quite High
Disease 1 46.76 Quite Low
Pressure Volume 2 Under Development 2 45.12 Quite Low
Injury 6 43.24 Quite Low
Cv General 3 Under Development 1 40.40 Quite Low
Cyanosis 1 26.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In human T cells, the four transmembrane┬ľdomain protein Orai1 (Ca2+ release┬ľactivated channel modulator) appears to be the predominant SOC channel (12), but the C-terminal region of STIM1 also interacts with other SOC channel candidates, such as transient receptor potential channels (TRPCs) 1, 2, and 4 (13).
STIM1 Binding (interacts) of channel in T cells associated with trp channel
1) Confidence 0.01 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442636 Disease Relevance 0.30 Pain Relevance 0.08

General Comments

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