INT237810

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.68
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Itpr3, Car2) nucleoplasm (Itpr3) transport (Itpr3)
lyase activity (Car2) endoplasmic reticulum (Itpr3) transmembrane transport (Itpr3)
Anatomy Link Frequency
reticulum 6
Itpr3 (Mus musculus)
Car2 (Mus musculus)
Pain Link Frequency Relevance Heat
member 8 4 93.80 High High
agonist 21 93.36 High High
cva 6 67.60 Quite High
TRP channel 1 42.88 Quite Low
imagery 7 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Hemorrhage 16 84.80 Quite High
Cv General 4 Under Development 6 83.76 Quite High
Death 4 77.24 Quite High
Disease 1 73.96 Quite High
Pressure Volume 2 Under Development 2 72.32 Quite High
Injury 6 70.44 Quite High
Cv General 3 Under Development 1 67.60 Quite High
Thrombosis 28 50.00 Quite Low
Coagulation Disorder 1 16.64 Low Low
Hemorrhage 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
2 to produce IP3, which induces calcium (Ca2+) release through IP3R3 located on the membrane of endoplasmic reticulum (ER).
IP3R3 Positive_regulation (induces) of Localization (release) of Ca2 in reticulum
1) Confidence 0.08 Published 2010 Journal Chemical Senses Section Body Doc Link PMC2805811 Disease Relevance 0 Pain Relevance 0.19
2 to produce IP3, which induces calcium (Ca2+) release through IP3R3 located on the membrane of endoplasmic reticulum (ER).
IP3 Positive_regulation (induces) of Localization (release) of Ca2 in reticulum
2) Confidence 0.07 Published 2010 Journal Chemical Senses Section Body Doc Link PMC2805811 Disease Relevance 0 Pain Relevance 0.19
IP3 induces the release of Ca2+ from the sarcoplasmatic reticulum (SR), which is thought to trigger the influx of extracellular Ca2+ by a mechanism known as store-operated Ca2+ entry (SOCE) (5, 6).
IP3 Positive_regulation (induces) of Localization (release) of Ca2 in reticulum
3) Confidence 0.03 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442636 Disease Relevance 0.68 Pain Relevance 0.08

General Comments

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