INT237811

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Esr1, Stim1) plasma membrane (Esr1, Stim1) transport (Stim1)
endoplasmic reticulum (Stim1) enzyme binding (Esr1) DNA binding (Esr1)
Anatomy Link Frequency
mast cells 1
Esr1 (Mus musculus)
Stim1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 21 81.72 Quite High
imagery 7 9.32 Low Low
ischemia 6 5.00 Very Low Very Low Very Low
cva 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
TRP channel 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombosis 28 50.00 Quite Low
Brain Hemorrhage 16 20.72 Low Low
Infarction 4 15.32 Low Low
Hemorrhage 15 6.64 Low Low
Cv General 4 Under Development 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Transient Ischemic Attack 3 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, mast cells lacking the major SOC channel Orai1 (22) show normal store content, suggesting a SOC channel–independent role of STIM1 in store refill, possibly through interaction with the IP3 receptors or SERCA pumps in the SR/ER.
ER Binding (interaction) of STIM1 in mast cells
1) Confidence 0.09 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442636 Disease Relevance 0 Pain Relevance 0.07

General Comments

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