INT237822

Context Info Confidence 0.54 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.27 Pain Relevance 0.08

transport (Stim1, Trpc1) plasma membrane (Stim1, Trpc1) cytoplasm (Stim1, Trpc1) endoplasmic reticulum (Stim1) cytoskeleton (Stim1) protein complex (Trpc1)

Anatomy Link Frequency platelets 1 Stim1 (Mus musculus) Trpc1 (Mus musculus)

Pain Link Frequency Relevance Heat TRP channel 1 98.36 agonist 21 60.48 cva 6 34.72 imagery 7 5.00 ischemia 6 5.00 anesthesia 2 5.00 Potency 2 5.00 Versed 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Coagulation Disorder 1 87.28 Thrombosis 28 75.04 Brain Hemorrhage 16 51.92 Cv General 4 Under Development 6 50.88 Death 4 44.36 Cyanosis 1 41.76 Disease 1 41.08 Pressure Volume 2 Under Development 2 39.44 Injury 6 37.56 Cv General 3 Under Development 1 34.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In platelets, STIM1 is expressed at high levels (14) and may contribute to SOCE by interacting with TRPC1 (15).

STIM1 Binding (interacting) of TRPC1 in platelets

1) Confidence 0.54 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442636 Disease Relevance 0.27 Pain Relevance 0.08

General Comments

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