INT237824

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.25
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Stim1) endoplasmic reticulum (Stim1) plasma membrane (Stim1)
cytoskeleton (Stim1) cytoplasm (Stim1)
Anatomy Link Frequency
mast cells 2
Stim1 (Mus musculus)
soc (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 42 82.04 Quite High
TRP channel 2 76.40 Quite High
cva 12 56.28 Quite High
imagery 14 5.00 Very Low Very Low Very Low
ischemia 12 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Hemorrhage 32 73.48 Quite High
Cv General 4 Under Development 12 72.44 Quite High
Death 8 65.92 Quite High
Disease 2 62.64 Quite High
Pressure Volume 2 Under Development 4 61.00 Quite High
Injury 12 59.12 Quite High
Cv General 3 Under Development 2 56.28 Quite High
Coagulation Disorder 2 50.16 Quite High
Thrombosis 56 50.00 Quite Low
Hemorrhage 30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stromal interaction molecule 1 (STIM1) is an SR/endoplasmic reticulum (ER)–resident protein necessary for the detection of ER Ca2+ depletion and the activation of SOC channels in T cells (8–10) and mast cells (11).
STIM1 Positive_regulation (activation) of SOC in mast cells
1) Confidence 0.26 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442636 Disease Relevance 0.62 Pain Relevance 0.11
Stromal interaction molecule 1 (STIM1) is an SR/endoplasmic reticulum (ER)–resident protein necessary for the detection of ER Ca2+ depletion and the activation of SOC channels in T cells (8–10) and mast cells (11).
Stromal interaction molecule 1 Positive_regulation (activation) of SOC in mast cells
2) Confidence 0.26 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442636 Disease Relevance 0.63 Pain Relevance 0.11

General Comments

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