INT237958

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.33
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TNFRSF10B)
TNFRSF10B (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 56 72.96 Quite High
antagonist 46 54.92 Quite High
cINOD 6 5.00 Very Low Very Low Very Low
qutenza 6 5.00 Very Low Very Low Very Low
COX-2 inhibitor 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 56 99.64 Very High Very High Very High
Apoptosis 280 99.04 Very High Very High Very High
Neuroblastoma 2 96.44 Very High Very High Very High
Glioblastoma 2 95.72 Very High Very High Very High
Renal Cancer 4 93.28 High High
Toxicity 6 78.72 Quite High
Cancer 132 68.72 Quite High
Reprotox - General 1 8 65.64 Quite High
Leukemia 10 64.40 Quite High
Lung Cancer 16 37.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
indicating a critical role of DR5 induction in this death process.
Regulation (role) of Positive_regulation (induction) of DR5 associated with death
1) Confidence 0.31 Published 2008 Journal PPAR Research Section Body Doc Link PMC2442903 Disease Relevance 1.07 Pain Relevance 0.06
In addition to upregulation of DR5 and reduction of c-FLIP, troglitazone
Regulation (troglitazone) of Positive_regulation (upregulation) of DR5
2) Confidence 0.20 Published 2008 Journal PPAR Research Section Body Doc Link PMC2442903 Disease Relevance 1.26 Pain Relevance 0.03

General Comments

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