INT237971

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.23
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.52
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TNFRSF10B)
TNFRSF10B (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 50 97.54 Very High Very High Very High
antagonist 46 95.84 Very High Very High Very High
cINOD 14 90.80 High High
agonist 56 77.84 Quite High
Inflammation 82 50.00 Quite Low
metalloproteinase 204 5.00 Very Low Very Low Very Low
cytokine 152 5.00 Very Low Very Low Very Low
chemokine 40 5.00 Very Low Very Low Very Low
qutenza 6 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 62 100.00 Very High Very High Very High
Apoptosis 296 97.92 Very High Very High Very High
Renal Cancer 4 94.80 High High
Herpes Simplex Virus 476 89.12 High High
Infection 208 88.24 High High
Lung Cancer 16 86.80 High High
INFLAMMATION 90 84.52 Quite High
Leukemia 12 76.72 Quite High
Reprotox - General 1 8 74.80 Quite High
Sarcoma 158 66.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The use of a DR5/Fc chimeric
Regulation (use) of Gene_expression (chimeric) of DR5
1) Confidence 0.23 Published 2008 Journal PPAR Research Section Body Doc Link PMC2442903 Disease Relevance 1.08 Pain Relevance 0.07
Though the selective COX-2 inhibitors cause only occasional deleterious effects, they have also been shown to exhibit some COX-2 independent effects such as up-regulation of death receptor 5 (DR5) expression, inhibition of survival signal pathways, and augmentation of apoptosis [43],[44].
Regulation (regulation) of Gene_expression (expression) of death receptor 5 associated with cox-2 inhibitor, apoptosis and death
2) Confidence 0.14 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 0.83 Pain Relevance 0.22
Though the selective COX-2 inhibitors cause only occasional deleterious effects, they have also been shown to exhibit some COX-2 independent effects such as up-regulation of death receptor 5 (DR5) expression, inhibition of survival signal pathways, and augmentation of apoptosis [43],[44].
Regulation (regulation) of Gene_expression (expression) of DR5 associated with cox-2 inhibitor, apoptosis and death
3) Confidence 0.14 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 0.83 Pain Relevance 0.22
the modulation of DR5 and c-FLIP expression is independent of PPAR?
Regulation (modulation) of Gene_expression (expression) of DR5
4) Confidence 0.14 Published 2008 Journal PPAR Research Section Body Doc Link PMC2442903 Disease Relevance 0.78 Pain Relevance 0.24

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox