INT237990

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.91
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl9)
Anatomy Link Frequency
neutrophils 2
Cxcl9 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 26 98.48 Very High Very High Very High
interstitial cystitis 41 81.04 Quite High
Inflammation 34 74.64 Quite High
chemokine 16 60.04 Quite High
cva 1 44.32 Quite Low
agonist 1 38.40 Quite Low
Crohn's disease 26 36.08 Quite Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 55 100.00 Very High Very High Very High
Colitis 71 96.92 Very High Very High Very High
Interstitial Cystitis 41 81.04 Quite High
Cystitis 70 78.60 Quite High
INFLAMMATION 32 74.64 Quite High
Inflammatory Bowel Disease 22 68.20 Quite High
Hemorrhage 1 44.32 Quite Low
Rupture 1 43.08 Quite Low
Paratuberculosis 20 42.68 Quite Low
Infection 5 26.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, the higher expression of CXCL9 in man and CXCL10 in mouse, during clinical and experimental disease, respectively, could be explained by these promoter differences or the imperfect correlation between clinical disease and the experimental mouse model used in this study.
Regulation (explained) of Gene_expression (expression) of CXCL9 associated with disease
1) Confidence 0.44 Published 2008 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC2583981 Disease Relevance 1.15 Pain Relevance 0.53
As with these innate immunity cells, neutrophils are compartmentalized in the MLN and tightly regulated to differentially express CXCL9 and CXCL11, CXCR3 and Th1-associated cytokines during Mycobacteria-mediated colitis.
Regulation (regulated) of Gene_expression (express) of CXCL9 in neutrophils associated with colitis and cytokine
2) Confidence 0.33 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2443107 Disease Relevance 0.76 Pain Relevance 0.05

General Comments

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