INT237999

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 3.49
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl11) signal transduction (Cxcr3) extracellular region (Cxcl11)
plasma membrane (Cxcr3) signal transducer activity (Cxcr3)
Cxcr3 (Mus musculus)
Cxcl11 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 26 99.68 Very High Very High Very High
chemokine 16 99.36 Very High Very High Very High
Inflammation 34 99.28 Very High Very High Very High
Crohn's disease 26 97.00 Very High Very High Very High
Inflammatory response 1 78.80 Quite High
Lasting pain 1 75.60 Quite High
interstitial cystitis 41 58.96 Quite High
pain pelvic 1 39.64 Quite Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 32 99.28 Very High Very High Very High
Cystitis 70 98.64 Very High Very High Very High
Disease 55 97.00 Very High Very High Very High
Colitis 71 95.24 Very High Very High Very High
Alagille Syndrome 2 84.16 Quite High
Paratuberculosis 20 78.44 Quite High
Pain 2 74.72 Quite High
Cancer 2 67.84 Quite High
Fever 1 66.32 Quite High
Overactive Bladder 1 65.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, CXCL9, CXCL10, and CXCL11 bind to a common receptor, CXCR3.
CXCR3 Binding (bind) of CXCL11
1) Confidence 0.45 Published 2008 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC2583981 Disease Relevance 1.64 Pain Relevance 0.61
CXCR3 interactions with CXCL9, CXCL10 and CXCL11 are important for the selective homing of Th1 effectors cells [10], which mediate mucosal immunity, inflammation, and colitis [11,12].
CXCR3 Binding (interactions) of CXCL11 associated with colitis and inflammation
2) Confidence 0.31 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2443107 Disease Relevance 1.86 Pain Relevance 0.51

General Comments

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