INT238005

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.38
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.73
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cxcr3, Cxcl10) extracellular space (Cxcl10) extracellular region (Cxcl10)
plasma membrane (Cxcr3) signal transducer activity (Cxcr3)
Anatomy Link Frequency
mast cells 2
Cxcr3 (Mus musculus)
Cxcl10 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 40 99.68 Very High Very High Very High
Inflammation 58 99.28 Very High Very High Very High
Crohn's disease 27 97.00 Very High Very High Very High
interstitial cystitis 82 93.76 High High
Inflammatory mediators 2 78.12 Quite High
chemokine 28 5.00 Very Low Very Low Very Low
Lasting pain 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
pain pelvic 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 56 99.28 Very High Very High Very High
Disease 71 97.00 Very High Very High Very High
Colitis 73 94.80 High High
Interstitial Cystitis 82 93.76 High High
Cystitis 140 92.08 High High
Alagille Syndrome 2 84.16 Quite High
Paratuberculosis 20 78.44 Quite High
Granuloma 1 60.60 Quite High
Inflammatory Bowel Disease 25 48.76 Quite Low
Oral Lichen Planus 2 45.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, the present study presents a scenario where CYP induction leads to increased numbers of both systemic and mucosal mast cells, partially through CXCL10-CXCR3 interactions.
CXCR3 Binding (interactions) of CXCL10 in mast cells
1) Confidence 0.38 Published 2008 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC2583981 Disease Relevance 0.94 Pain Relevance 0.46
Taken together, the present study presents a scenario where CYP induction leads to increased numbers of both systemic and mucosal mast cells, partially through CXCL10-CXCR3 interactions.
CXCR3 Binding (interactions) of CXCL10 in mast cells
2) Confidence 0.38 Published 2008 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC2583981 Disease Relevance 0.94 Pain Relevance 0.46
CXCR3 interactions with CXCL9, CXCL10 and CXCL11 are important for the selective homing of Th1 effectors cells [10], which mediate mucosal immunity, inflammation, and colitis [11,12].
CXCR3 Binding (interactions) of CXCL10 associated with colitis and inflammation
3) Confidence 0.28 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2443107 Disease Relevance 1.85 Pain Relevance 0.51

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox