INT238013

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MLN) cell-cell signaling (MLN)
Anatomy Link Frequency
colon 2
MLN (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 25 87.32 High High
Inflammation 10 76.04 Quite High
cytokine 12 36.20 Quite Low
chemokine 4 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
behavioral therapy 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 40 87.32 High High
INFLAMMATION 8 76.04 Quite High
Colitis 69 69.48 Quite High
Constipation 13 55.60 Quite High
Fecal Incontinence 3 55.56 Quite High
Functional Bowel Disorder 2 54.52 Quite High
Gastrointestinal Disease 1 50.00 Quite Low
Inflammatory Bowel Disease 19 41.96 Quite Low
Paratuberculosis 20 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that the colon motilin receptors may have reduced affinity for erythromycin compared to the antral nerves or the expression of motilin receptor may be reduced in the colon.
Negative_regulation (reduced) of Gene_expression (expression) of motilin in colon
1) Confidence 0.42 Published 2008 Journal BMC Gastroenterol Section Body Doc Link PMC2529327 Disease Relevance 0.17 Pain Relevance 0
In the present study, we show that CXCL9 and CXCL11 are predominantly produced by DCs in the MLN as well as in PP and to a lesser degree in the intestinal LP.
Negative_regulation (degree) of Gene_expression (produced) of MLN
2) Confidence 0.03 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2443107 Disease Relevance 0.47 Pain Relevance 0.08

General Comments

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