INT238036

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.66
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (ENPP1) extracellular space (ENPP1) small molecule metabolic process (ENPP1)
plasma membrane (ENPP1)
ENPP1 (Homo sapiens)
OPLL (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 4 59.40 Quite High
antagonist 12 5.00 Very Low Very Low Very Low
agonist 8 5.00 Very Low Very Low Very Low
spinal inflammation 8 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heterotopic Ossification 60 75.92 Quite High
Spinal Cord Diseases 8 61.12 Quite High
Osteoporosis 32 38.08 Quite Low
Disease 28 5.00 Very Low Very Low Very Low
Metabolic Disorder 12 5.00 Very Low Very Low Very Low
Rickets 8 5.00 Very Low Very Low Very Low
Low Back Pain 8 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 8 5.00 Very Low Very Low Very Low
Hypercalcemia 4 5.00 Very Low Very Low Very Low
Diffuse Idiopathic Skeletal Hyperostosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nakamura et al reported that the nucleotide pyrophosphatase gene (NPPS), which has been identified as a cause in a mouse model of OPLL [18], is also associated with OPLL [16].
NPPS Binding (associated) of OPLL
1) Confidence 0.27 Published 2008 Journal Eur Spine J Section Body Doc Link PMC2443260 Disease Relevance 0.18 Pain Relevance 0.03
Nakamura et al reported that the nucleotide pyrophosphatase gene (NPPS), which has been identified as a cause in a mouse model of OPLL [18], is also associated with OPLL [16].
NPPS Binding (associated) of OPLL
2) Confidence 0.20 Published 2008 Journal Eur Spine J Section Body Doc Link PMC2443260 Disease Relevance 0.18 Pain Relevance 0.03
Nakamura et al reported that the nucleotide pyrophosphatase gene (NPPS), which has been identified as a cause in a mouse model of OPLL [18], is also associated with OPLL [16].
NPPS Binding (associated) of OPLL
3) Confidence 0.20 Published 2008 Journal Eur Spine J Section Body Doc Link PMC2443260 Disease Relevance 0.18 Pain Relevance 0.03
The results demonstrated that the IVS20-11delT allele in the NPPS gene and the A861G polymorphism in the leptin receptor gene are associated with more extensive OPLL, but not with its occurrence rate [25].
NPPS gene Binding (associated) of OPLL
4) Confidence 0.01 Published 2008 Journal Eur Spine J Section Body Doc Link PMC2443260 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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