INT238217

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (STAT3, Bcar1) plasma membrane (STAT3, Bcar1) nucleoplasm (STAT3)
DNA binding (STAT3) signal transducer activity (STAT3) cell proliferation (STAT3)
Anatomy Link Frequency
myocardium 2
STAT3 (Homo sapiens)
Bcar1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 55.04 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Acupuncture 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Squamous Cell Neoplasms 1 7.68 Low Low
Adhesions 8 5.00 Very Low Very Low Very Low
Coronary Heart Disease 7 5.00 Very Low Very Low Very Low
Hypertrophy 6 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 2 5.00 Very Low Very Low Very Low
Fibrosis 1 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Presence of STAT3 at FAC sites has been demonstrated previously7 to enhance FAK activity.39 Furthermore, evidence exists for STAT3 interaction with other components of the cytoskeleton, including paxillin, p130Cas, and stathmin.10 Therefore, STAT3 presence in the MSK of 48 h PO myocardium is indicative of its possible role at the FAC for cytoskeletal remodeling, independent of its transcriptional role.
Positive_regulation (exists) of STAT3 Binding (interaction) of p130Cas in myocardium
1) Confidence 0.04 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2443357 Disease Relevance 0 Pain Relevance 0.03

General Comments

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