INT238250

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.16
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (C3) extracellular space (C3) extracellular region (C3)
C3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 190 100.00 Very High Very High Very High
chemokine 2 92.16 High High
Spinal cord 57 90.12 High High
Central nervous system 29 47.92 Quite Low
Inflammatory response 4 43.76 Quite Low
Inflammation 28 25.52 Quite Low
imagery 5 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spinal Cord Injury 70 90.12 High High
Pressure And Volume Under Development 184 89.04 High High
Injury 57 85.48 High High
Acute Liver Failure 56 76.64 Quite High
Cerebral Edema 38 75.84 Quite High
Liver Failure 4 72.08 Quite High
Death 6 59.88 Quite High
Central Nervous System Disease 28 47.92 Quite Low
Hyperammonemia 8 46.88 Quite Low
INFLAMMATION 32 43.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data confirm C3 expression by PMNs in culture, and demonstrate the expression of C1q and C4 by PMNs, providing a more complete characterization of PMN expression of the early complement proteins in culture.
Regulation (confirm) of Gene_expression (expression) of C3
1) Confidence 0.27 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2443364 Disease Relevance 0.31 Pain Relevance 0.16
showed no additive effects on the expression of complement (C3) genes, although individually these cytokines significantly enhanced C3 gene expression [41].
Neg (no) Regulation (effects) of Gene_expression (expression) of C3 associated with cytokine
2) Confidence 0.09 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2964656 Disease Relevance 0.89 Pain Relevance 0.40
showed no additive effects on the expression of complement (C3) genes, although individually these cytokines significantly enhanced C3 gene expression [41].
Neg (no) Regulation (effects) of Gene_expression (expression) of C3 associated with cytokine
3) Confidence 0.04 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2964656 Disease Relevance 0.96 Pain Relevance 0.42

General Comments

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