INT238253

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Context Info
Confidence 0.37
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.76
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (C3) extracellular space (C3) extracellular region (C3)
Anatomy Link Frequency
spinal cord 1
C3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 1 96.20 Very High Very High Very High
antagonist 1 95.32 Very High Very High Very High
Spinal cord 57 94.56 High High
Central nervous system 29 85.40 High High
Inflammation 8 75.44 Quite High
cytokine 4 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 4 97.04 Very High Very High Very High
Cv Unclassified Under Development 1 96.20 Very High Very High Very High
Spinal Cord Injury 70 94.88 High High
Injury 57 90.40 High High
Central Nervous System Disease 28 85.40 High High
INFLAMMATION 8 75.44 Quite High
Disease 4 56.92 Quite High
Drug Induced Neurotoxicity 3 5.00 Very Low Very Low Very Low
Cicatrix 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As demonstrated in previous studies that showed PMNs synthesis and release of C3 in culture [16,17], and in the present study that showed PMNs express high levels of C3 mRNAs and proteins in vitro and in the injured spinal cord, it is likely that PMNs may contribute to the elevated level of complement involved in post-injury neurogenesis.
Localization (release) of C3 in spinal cord associated with spinal cord injury, injury, neurodegenerative disease and spinal cord
1) Confidence 0.37 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2443364 Disease Relevance 1.76 Pain Relevance 0.41

General Comments

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