INT238263

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.57
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cd59) plasma membrane (Cd59)
pma (Mus musculus)
Cd59 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 8 100.00 Very High Very High Very High
cytokine 8 71.96 Quite High
Spinal cord 114 50.00 Quite Low
Central nervous system 58 5.00 Very Low Very Low Very Low
Inflammation 16 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Buprenorphine 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 4 99.84 Very High Very High Very High
Lifespan 2 97.24 Very High Very High Very High
Injury 114 47.68 Quite Low
Spinal Cord Injury 140 7.24 Low Low
Central Nervous System Disease 56 5.00 Very Low Very Low Very Low
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 6 5.00 Very Low Very Low Very Low
Cicatrix 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, previous studies have shown that PMA and PKC activity enhanced CD59 expression in cancer cells and therefore, increased the survival of these cells [30,31].
PMA Positive_regulation (enhanced) of Gene_expression (expression) of CD59 associated with kinase c and cancer
1) Confidence 0.02 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2443364 Disease Relevance 0.29 Pain Relevance 0.13
The contrasting PMA-induced CD59 expression in PMNs and cancer cells suggests different responses by these cell types to PMA stimulation.
PMA Positive_regulation (induced) of Gene_expression (expression) of CD59 associated with cancer
2) Confidence 0.02 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2443364 Disease Relevance 0.29 Pain Relevance 0.12

General Comments

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