INT238311

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.48
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tfrc) peptidase activity (Tfrc) mitochondrion (Tfrc)
aging (Tfrc) extracellular region (Tfrc) cytoplasmic membrane-bounded vesicle (Tfrc)
Anatomy Link Frequency
liver 2
Tfrc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 42 96.76 Very High Very High Very High
Central nervous system 3 89.84 High High
Bile 3 59.04 Quite High
Inflammation 5 10.24 Low Low
agonist 10 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Abscess 6 80.28 Quite High
Targeted Disruption 6 68.88 Quite High
Increased Venous Pressure Under Development 6 58.80 Quite High
Pressure And Volume Under Development 2 58.00 Quite High
Diabetes Mellitus 5 57.08 Quite High
Disease 7 55.72 Quite High
Obesity 9 53.88 Quite High
Injury 18 30.64 Quite Low
Alzheimer's Dementia 3 14.32 Low Low
INFLAMMATION 5 10.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Physical preconditioning significantly reduced insulin levels in both groups (TR: 0.54 ± 0.1 and TRD: 1.24 ± 0.3 ng/ml) as compared to sedentary animals (SD: 0.87 ± 0.1 and SDD: 2.57 ± 0.3 ng/ml).
Negative_regulation (reduced) of Gene_expression (levels) of TR
1) Confidence 0.16 Published 2008 Journal BMC Physiol Section Abstract Doc Link PMC2443377 Disease Relevance 0.28 Pain Relevance 0
2, which lacks the T3-binding domain and therefore acts as the dominant negative inhibitor of TR?
Negative_regulation (inhibitor) of Neg (negative) Gene_expression (negative) of TR
2) Confidence 0.10 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2977073 Disease Relevance 0.12 Pain Relevance 0.04
Immunohistology also showed a similar pattern of protein expression in TR?
Negative_regulation (pattern) of Gene_expression (expression) of TR
3) Confidence 0.09 Published 2010 Journal Cell Tissue Res Section Abstract Doc Link PMC2977073 Disease Relevance 0.08 Pain Relevance 0.04
Similar to the observations in the liver tissue during APR, a reduction in gene expression of DOR and TR?
Negative_regulation (reduction) of Gene_expression (expression) of TR in liver
4) Confidence 0.09 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2977073 Disease Relevance 0 Pain Relevance 0.13

General Comments

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