INT238314

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pik3cb, Slc2a4) endosome (Slc2a4) cytosol (Pik3cb)
signal transduction (Pik3cb) cell adhesion (Pik3cb) plasma membrane (Slc2a4)
Pik3cb (Rattus norvegicus)
Slc2a4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 1 93.88 High High
agonist 10 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperinsulinism 3 87.48 High High
Insulin Resistance 3 86.12 High High
Stress 2 46.60 Quite Low
Obesity 9 42.24 Quite Low
Body Weight 3 22.28 Low Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The IR phosphorylation reduces its ability to activate PI3K leading to decrease of the glucose transporters GLUT-4 translocation to the cellular membrane resulting in impairment of glucose uptake [31].
PI3K Negative_regulation (decrease) of Localization (translocation) of GLUT-4
1) Confidence 0.06 Published 2008 Journal BMC Physiol Section Body Doc Link PMC2443377 Disease Relevance 0.25 Pain Relevance 0.05

General Comments

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