INT238359

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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.23
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ADAMTS4) extracellular space (ADAMTS4) extracellular region (ADAMTS4)
proteinaceous extracellular matrix (ADAMTS4)
ADAMTS4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 22 98.52 Very High Very High Very High
Pain 28 85.00 Quite High
metalloproteinase 16 62.12 Quite High
Mechanotransduction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Tendinopathy 20 85.52 High High
Targeted Disruption 2 40.00 Quite Low
Rupture 8 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Bone Cancer 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Amputation 2 5.00 Very Low Very Low Very Low
Cadaver 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It may thus represent further processing and release of ADAMTS-4 from the cells in response to these cytokines, analogous to some of the effects reported in other model systems (Patwari et al., 2005).
Localization (release) of ADAMTS-4 associated with cytokine
1) Confidence 0.38 Published 2008 Journal Matrix Biol Section Body Doc Link PMC2443387 Disease Relevance 0.07 Pain Relevance 0.12
Increased levels of immunoreactive proteins consistent with mature and processed forms of ADAMTS-4 were detected in TGF-?
Localization (forms) of ADAMTS-4
2) Confidence 0.38 Published 2008 Journal Matrix Biol Section Abstract Doc Link PMC2443387 Disease Relevance 0.16 Pain Relevance 0.23

General Comments

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