INT238366

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrm2) plasma membrane (Chrm2) signal transducer activity (Chrm2)
Anatomy Link Frequency
M1 macrophages 2
Chrm2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 66 99.36 Very High Very High Very High
agonist 8 89.36 High High
cytokine 13 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 76 99.36 Very High Very High Very High
Cancer 81 97.68 Very High Very High Very High
Colitis 6 5.00 Very Low Very Low Very Low
Colon Cancer 6 5.00 Very Low Very Low Very Low
Atherosclerosis 5 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Repression 3 5.00 Very Low Very Low Very Low
Insulin Resistance 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of the nuclear peroxisome proliferator-activated receptors (PPARs) is regulated by M1- or M2-inducing stimuli, and these receptors are generally considered to counteract inflammatory M1 macrophages, while actively promoting M2 activation.
Positive_regulation (promoting) of Positive_regulation (activation) of M2 in M1 macrophages associated with inflammation
1) Confidence 0.05 Published 2008 Journal PPAR Research Section Abstract Doc Link PMC2443396 Disease Relevance 0.82 Pain Relevance 0.26

General Comments

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