INT238429

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.55
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (E2F2) nucleus (E2F2) DNA binding (E2F2)
transcription factor binding (E2F2)
E2F2 (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 2 97.72 Very High Very High Very High
qutenza 130 69.12 Quite High
agonist 12 61.36 Quite High
Inflammation 9 6.08 Low Low
Pain 1 5.40 Low Low
COX2 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 62 95.76 Very High Very High Very High
Retinoblastoma 2 93.44 High High
Obesity 4 86.68 High High
Pancreatic Cancer 2 65.44 Quite High
Breast Cancer 4 65.08 Quite High
Colon Cancer 10 50.92 Quite High
Small Cell Lung Cancer 63 50.00 Quite Low
Reprotox - General 1 6 44.92 Quite Low
Squamous Cell Carcinoma 1 43.88 Quite Low
Injury 2 43.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The second subclass, E2F4 and E2F5, are referred to as the “repressor” E2Fs because they repress the transcription of E2F target proliferative genes.
Transcription (transcription) of E2F
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2857654 Disease Relevance 0.07 Pain Relevance 0.24
When

hyperphosphorylated, pRB cannot bind to E2F transcription factors that can

Transcription (transcription) of E2F
2) Confidence 0.06 Published 2008 Journal PPAR Research Section Body Doc Link PMC2443425 Disease Relevance 0.10 Pain Relevance 0
preadipocytes via suppression of the transcriptional activity of E2F/DP
Transcription (activity) of E2F
3) Confidence 0.05 Published 2008 Journal PPAR Research Section Body Doc Link PMC2443425 Disease Relevance 0.39 Pain Relevance 0.08

General Comments

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