INT238630

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (EPB41, Cask) cytoplasm (EPB41, Cask) nucleus (EPB41, Cask)
plasma membrane (EPB41, Cask) Golgi apparatus (EPB41) intracellular (Cask)
EPB41 (Homo sapiens)
Cask (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cerebral cortex 3 40.16 Quite Low
midbrain 2 38.56 Quite Low
tetrodotoxin 10 5.00 Very Low Very Low Very Low
Glutamate receptor 3 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
GABAergic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Cleft Palate 2 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 1 5.00 Very Low Very Low Very Low
Aids-related Complex 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because protein 4.1 interacts with spectrin and promotes the interaction between spectrin and filamentous actin, reduction of the interaction between CASK and protein 4.1 by SUMOylation would be expected to attenuate the association between CASK and filamentous actin.
Negative_regulation (reduction) of protein 4.1 Binding (interaction) of CASK
1) Confidence 0.45 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2447900 Disease Relevance 0 Pain Relevance 0

General Comments

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