INT238642

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, Ada) plasma membrane (TNF, Ada) intracellular (TNF)
extracellular matrix organization (TNF) cytoplasm (Ada) cytosol (Ada)
TNF (Homo sapiens)
Ada (Mus musculus)
Pain Link Frequency Relevance Heat
Infliximab 35 100.00 Very High Very High Very High
Etanercept 31 100.00 Very High Very High Very High
Adalimumab 8 100.00 Very High Very High Very High
Crohn's disease 14 88.08 High High
Inflammation 5 55.28 Quite High
Inflammatory stimuli 1 50.64 Quite High
cytokine 3 46.12 Quite Low
imagery 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 16 87.44 High High
Apoptosis 48 79.32 Quite High
Ileitis 1 74.04 Quite High
INFLAMMATION 6 55.28 Quite High
Liver Failure 1 34.52 Quite Low
Colitis 36 30.48 Quite Low
Inflammatory Bowel Disease 3 23.72 Low Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
 ; however, membrane-bound TNF is not, or less, recognized by ETC 28, whereas IFX and ADA also bind to this uncleaved form.
TNF Binding (bind) of ADA associated with infliximab, adalimumab and etanercept
1) Confidence 0.03 Published 2008 Journal International Journal of Medical Sciences Section Body Doc Link PMC2452978 Disease Relevance 0.86 Pain Relevance 0.84

General Comments

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