INT238713

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Context Info
Confidence 0.43
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.70
Pain Relevance 1.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (CHPT1) lipid metabolic process (CHPT1)
Anatomy Link Frequency
amygdala 2
CHPT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain threshold 33 100.00 Very High Very High Very High
amygdala 81 99.98 Very High Very High Very High
Inflammation 43 98.72 Very High Very High Very High
Hyperalgesia 23 98.16 Very High Very High Very High
Pain 75 97.54 Very High Very High Very High
c fibre 11 93.92 High High
Cold hyperalgesia 10 84.08 Quite High
unmyelinated 1 60.32 Quite High
burning pain 2 59.44 Quite High
Neuropeptide 24 50.00 Quite Low
Disease Link Frequency Relevance Heat
Pain 85 100.00 Very High Very High Very High
Reflex Sympathetic Dystrophy 132 99.52 Very High Very High Very High
INFLAMMATION 35 98.72 Very High Very High Very High
Conjunctivitis 4 98.32 Very High Very High Very High
Hyperalgesia 35 98.16 Very High Very High Very High
Pruritus 6 95.04 Very High Very High Very High
Disease 18 83.12 Quite High
Nociception 6 82.80 Quite High
Hypersensitivity 38 76.92 Quite High
Conjunctiva Disease 10 58.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In other words, we observed lower amygdala activation when subjects were actively engaged in the CPT compared to when they passively waited for the same thermal stimuli (Fig. 1B).
Positive_regulation (activation) of Gene_expression (engaged) of CPT in amygdala associated with amygdala
1) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2993966 Disease Relevance 0.09 Pain Relevance 0.60
The hypothesis of cold pain hyperalgesia being caused by a combination of inflammation and A-delta-fibre degeneration is emphasised by the incomplete recovery of CPT in chronic CRPS.
Positive_regulation (recovery) of Gene_expression (recovery) of CPT associated with pain, pain threshold, hyperalgesia, reflex sympathetic dystrophy and inflammation
2) Confidence 0.20 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2453233 Disease Relevance 1.87 Pain Relevance 1.37
When a total CPT score ?
Positive_regulation (When) of Gene_expression (score) of CPT
3) Confidence 0.07 Published 2011 Journal Molecular Vision Section Body Doc Link PMC3021574 Disease Relevance 0.74 Pain Relevance 0

General Comments

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