INT23881

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Context Info
Confidence 0.52
First Reported 1986
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 2.48
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Bcar1) plasma membrane (Bcar1) cytoplasm (Bcar1)
Anatomy Link Frequency
plasma 1
brain 1
central nervous system 1
Bcar1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Catecholamine 22 100.00 Very High Very High Very High
Pain 1 99.92 Very High Very High Very High
Central nervous system 1 99.68 Very High Very High Very High
Inflammation 14 99.40 Very High Very High Very High
Analgesic 2 98.24 Very High Very High Very High
IPN 1 89.96 High High
agonist 41 89.52 High High
medulla 1 87.12 High High
Neuropeptide 2 75.00 Quite High
Thermal hyperalgesia 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 6 100.00 Very High Very High Very High
Pain 1 99.92 Very High Very High Very High
INFLAMMATION 15 99.40 Very High Very High Very High
Parkinson's Disease 9 97.58 Very High Very High Very High
Sprains And Strains 3 95.80 Very High Very High Very High
Inflammatory Pain 1 89.96 High High
Nociception 1 89.60 High High
Ganglion Cysts 1 84.56 Quite High
Pressure Volume 2 Under Development 1 80.52 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 78.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Six ketoprofen (CAS 22071-15-4) alkylazacycloalkan-2-one ester derivatives (I-VI) were synthesized and evaluated for their anti-inflammatory, analgesic, and ulcerogenic activities after oral administration.
Gene_expression (synthesized) of CAS associated with inflammation and analgesic
1) Confidence 0.52 Published 2002 Journal Arzneimittelforschung Section Abstract Doc Link 12572528 Disease Relevance 0.36 Pain Relevance 0.22
CAs are also present in the central nervous system and control anion concentrations.
Gene_expression (present) of CAs in central nervous system associated with central nervous system
2) Confidence 0.52 Published 2005 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 15743922 Disease Relevance 0.67 Pain Relevance 0.47
The results indicate that plasma levels of CAs but not NPY are useful indices of SNA in conscious rats.
Gene_expression (levels) of CAs in plasma associated with catecholamine
3) Confidence 0.38 Published 1986 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 2434735 Disease Relevance 0.63 Pain Relevance 0.33
In 10-s illumination of UV, the Calcium frequency is increased, resulting in more CaS (Figure 6B, right), followed by a decrease in 10?
Gene_expression (resulting) of CaS
4) Confidence 0.31 Published 2010 Journal Frontiers in Neural Circuits Section Body Doc Link PMC2876879 Disease Relevance 0 Pain Relevance 0.23
s UV, the cell fires CaS at a wide range of frequencies between 1–3?
Gene_expression (fires) of CaS
5) Confidence 0.31 Published 2010 Journal Frontiers in Neural Circuits Section Body Doc Link PMC2876879 Disease Relevance 0 Pain Relevance 0.08
The present study was designed to gain further insight into the possible role of islet TH in CAs synthesis and insulin secretion in vivo.
Gene_expression (synthesis) of CAs associated with catecholamine
6) Confidence 0.29 Published 2003 Journal BMC Endocr Disord Section Body Doc Link PMC153518 Disease Relevance 0 Pain Relevance 0.34
In an azidothymidine neurotoxicity model in rats, mildronate suppressed the neuroinflammatory and apoptotic processes in brain tissue by protecting the abnormal expression of cytochrome oxidase c, caspase-3, iNOS, cellular apoptosis susceptibility (CAS) protein and glial fibrillary acidic protein (GFAP) [37].
Gene_expression (expression) of CAS in brain associated with parkinson's disease and apoptosis
7) Confidence 0.15 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000094 Disease Relevance 0.58 Pain Relevance 0
Health care delivery organizations such as primary care clinics are an example of CAS (Stroebel et al 2005).
Gene_expression (example) of CAS
8) Confidence 0.12 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2686326 Disease Relevance 0.24 Pain Relevance 0.03

General Comments

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