INT238868

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.73
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LPL) small molecule metabolic process (LPL) extracellular region (LPL)
plasma membrane (LPL) lipid metabolic process (LPL)
Anatomy Link Frequency
adipose tissue 2
LPL (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 5 5.00 Very Low Very Low Very Low
Catecholamine 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 99 100.00 Very High Very High Very High
Rheumatoid Arthritis 5 5.00 Very Low Very Low Very Low
Insulin Resistance 3 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Wound Healing 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Calcification 1 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exposure to 10 nM ouabain for two days did not significantly change PPARG or LPL expression (Fig. 5A), but a four-day exposure resulted in a 2.5-fold decrease in PPARG and 3.7-fold decrease in LPL expression (Fig. 5B, p<0.02) compared to untreated AD.
Negative_regulation (decrease) of Gene_expression (expression) of LPL
1) Confidence 0.15 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2581599 Disease Relevance 0 Pain Relevance 0
However, it remains to be elucidated whether an impaired adipose tissue LPL activity during ?
Spec (whether) Negative_regulation (impaired) of Spec (whether) Gene_expression (activity) of LPL in adipose tissue associated with obesity
2) Confidence 0.11 Published 2008 Journal Diabetes Section Body Doc Link PMC2453623 Disease Relevance 0.73 Pain Relevance 0

General Comments

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