INT239059

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Context Info
Confidence 0.33
First Reported 2008
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 2.73
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Mbl2) extracellular region (Mbl2)
Mbl2 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 75 99.04 Very High Very High Very High
rheumatoid arthritis 275 95.04 Very High Very High Very High
Inflammation 40 64.20 Quite High
spinal inflammation 5 22.56 Low Low
ischemia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Juvenile Chronic Polyarthritis 40 99.04 Very High Very High Very High
Arthritis 105 98.06 Very High Very High Very High
Disease 145 97.16 Very High Very High Very High
Rheumatoid Arthritis 275 95.04 Very High Very High Very High
Infection 30 83.52 Quite High
Systemic Lupus Erythematosus 5 68.48 Quite High
Autoimmune Disease 5 65.12 Quite High
INFLAMMATION 35 64.20 Quite High
Spondylarthropathies 5 24.88 Low Low
Low Back Pain 5 22.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients were stratified according to remission status (active/remission) to explore further the association between CRP levels and MBL2 genotype in oligoarthritis patients.
MBL2 Binding (association) of
1) Confidence 0.33 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2453777 Disease Relevance 0.27 Pain Relevance 0.03
Multivariate binominal logistic regression was used to study the association between MBL2 genotype and remission status (active/remission) after adjustment for disease duration.
MBL2 Binding (association) of associated with disease
2) Confidence 0.33 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2453777 Disease Relevance 0.10 Pain Relevance 0
In that study no association between MBL2 codon 54 mutations and JIA was found.
MBL2 Neg (no) Binding (association) of associated with arthritis
3) Confidence 0.32 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2453777 Disease Relevance 0.50 Pain Relevance 0.19
The remaining clinical and laboratory variables, such as arthritis severity index, presence of radiographic erosions and antinuclear antibody positivity, were not associated with MBL2 genotypes.


MBL2 Binding (associated) of associated with arthritis
4) Confidence 0.32 Published 2008 Journal Arthritis Res Ther Section Abstract Doc Link PMC2453777 Disease Relevance 0.64 Pain Relevance 0.13
In addition, no association of MBL2 haplotypes was found between the subgroups of patients with JIA and control individuals.
MBL2 Neg (no) Binding (association) of associated with arthritis
5) Confidence 0.32 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2453777 Disease Relevance 1.22 Pain Relevance 0.40

General Comments

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