INT239064

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.59
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Mbl1) extracellular region (Mbl1)
Anatomy Link Frequency
synovial fluid 1
Mbl1 (Mus musculus)
IgG (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 110 100.00 Very High Very High Very High
Inflammation 16 96.60 Very High Very High Very High
ischemia 2 41.60 Quite Low
Arthritis 30 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 110 100.00 Very High Very High Very High
INFLAMMATION 14 96.60 Very High Very High Very High
Disease 58 95.44 Very High Very High Very High
Uveitis 6 75.40 Quite High
Coronary Artery Disease 4 75.12 Quite High
Arthritis 42 64.52 Quite High
Reperfusion Injury 2 40.88 Quite Low
Diabetes Mellitus 2 39.04 Quite Low
Infection 12 29.44 Quite Low
Apoptosis 2 29.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of MBL to agalactosyl IgG immune complexes may result in local complement activation and subsequent increased inflammation and thus active disease, whereas this is absent in the presence of very low levels of MBL [40].
MBL Binding (Binding) of IgG associated with inflammation and disease
1) Confidence 0.03 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2453777 Disease Relevance 1.25 Pain Relevance 0.37
MBL is present in synovial fluid and can bind potential causative agents in JRA including micro-organisms, cellular debris, and agalactosyl IgG (IgG-G0) [38,39].
MBL Binding (bind) of IgG in synovial fluid associated with rheumatoid arthritis
2) Confidence 0.03 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2453777 Disease Relevance 1.33 Pain Relevance 0.41

General Comments

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