INT23913

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Context Info
Confidence 0.15
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.80
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ttr) extracellular space (Ttr) extracellular region (Ttr)
Anatomy Link Frequency
liver 2
Ttr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 7 99.96 Very High Very High Very High
alcohol 2 90.88 High High
Neuropathic pain 2 85.88 High High
anesthesia 1 85.36 High High
diabetic neuropathy 4 81.80 Quite High
Inflammation 6 73.12 Quite High
Inflammatory response 4 52.96 Quite High
Bioavailability 5 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 16 99.96 Very High Very High Very High
Sepsis 10 96.20 Very High Very High Very High
Injury 9 91.08 High High
Wound Healing 7 89.80 High High
Neuropathic Pain 2 85.88 High High
Diabetic Neuropathy 4 81.80 Quite High
Burns 7 79.04 Quite High
Appetite Loss 19 75.00 Quite High
Disease 22 74.64 Quite High
INFLAMMATION 9 73.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In CP, transthyretin levels were decreased in 37%, transferrin in 27%, and albumin in 12% of patients.
Negative_regulation (decreased) of Gene_expression (levels) of transthyretin associated with chronic pancreatitis
1) Confidence 0.15 Published 2002 Journal Clin. Chem. Lab. Med. Section Abstract Doc Link 12553437 Disease Relevance 1.35 Pain Relevance 0.61
The levels of albumin mRNA and transthyretin mRNA (also called prealbumin) decreased to about 80% of normal and the level of transferrin mRNA did not change significantly.
Negative_regulation (decreased) of Gene_expression (levels) of transthyretin mRNA
2) Confidence 0.14 Published 1987 Journal J Trauma Section Abstract Doc Link 2435922 Disease Relevance 0.23 Pain Relevance 0.09
In the liver, the rate of synthesis of selected proteins (i.e., albumin, transferrin, prealbumin, retinol-binding protein, and fibronectin) is decreased, whereas acute phase protein synthesis is accelerated [94].
Negative_regulation (decreased) of Gene_expression (synthesis) of prealbumin in liver
3) Confidence 0.07 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2861661 Disease Relevance 1.22 Pain Relevance 0.18

General Comments

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