INT239157
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Further analysis of the effects of rilmenidine on primary neurons confirmed that rilmenidine does not act to upregulate autophagy via inactivation of the mTOR pathway. | |||||||||||||||
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In addition, the reduction in PI3K and mTOR signaling and subsequent attenuation of anabolism may simulate a stressful situation and upregulate general defense and repair systems, which, in the long term, extend lifespan. | |||||||||||||||
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General Comments
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