INT239158
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Of note, the use of PQ2+ as a toxicant was particularly advantageous in our model because in contrast to neuron-specific toxicants such as MPP+, PQ2+ is capable of inactivating m-aconitase in both mixed neuronal/glial cultures and near pure astrocytic cultures [30]. | |||||||||||||||
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These transgenics exhibit lower basal levels of liver mitochondrial SOD2 mRNA and protein, lower SOD2 activity levels, reduced lipid oxidation, and increased aconitase activity in mitochondria compared with wild-type mice. | |||||||||||||||
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General Comments
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