INT239184

Context Info Confidence 0.21 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.13 Pain Relevance 0

cytosol (Msr1) mitochondrion (Msra) oxidoreductase activity (Msra) aging (Msra) nucleus (Msra) plasma membrane (Msr1)

Msr1 (Mus musculus) Msra (Mus musculus)

Pain Link Frequency Relevance Heat tolerance 3 5.00 Inflammation 2 5.00 Paracetamol 1 5.00 cerebral cortex 1 5.00 withdrawal 1 5.00 ischemia 1 5.00

Disease Link Frequency Relevance Heat Stress 93 73.08 Shock 7 60.12 Aging 37 50.00 Disease 4 33.68 Cancer 15 29.96 Lifespan 22 15.20 Targeted Disruption 35 5.00 Death 5 5.00 Toxicity 3 5.00 Apoptosis 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The methionine sulfoxide reductase (Msr) enzymes function by reducing oxidized methionine (MetO) residues, acting as an antioxidant, and restoring function to damaged proteins.

Msr Negative_regulation (reducing) of MetO

1) Confidence 0.21 Published 2006 Journal Age (Dordr) Section Body Doc Link PMC2464727 Disease Relevance 0.13 Pain Relevance 0

General Comments

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