INT239218

Context Info Confidence 0.04 First Reported 2008 Last Reported 2011 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 2.21 Pain Relevance 0.10

transport (Cacna1s) plasma membrane (Cacna1s) cytoplasm (Cacna1s)

Anatomy Link Frequency brachial artery 1 Cacna1s (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 50 68.36 fibrosis 2 40.96 cytokine 10 5.00 bradykinin 10 5.00 rheumatoid arthritis 5 5.00 Kinase C 5 5.00 Chronic pancreatitis 4 5.00 Inflammatory response 4 5.00 tolerance 4 5.00 Angina 2 5.00

Disease Link Frequency Relevance Heat Syndrome 77 100.00 Cytomegalovirus Infection 15 99.98 Coronary Artery Disease 2 97.96 Heart Rate Under Development 3 89.84 Autoimmune Disease 14 86.40 Cardiovascular Disease 7 84.48 Disease 42 78.96 Sprains And Strains 18 76.72 Stress 10 72.12 Sialadenitis 8 71.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It has to be noted that even if no significant improvement in coronary endothelial function was detected, since reduced FMD of the brachial artery is associated with high cardiovascular event rate, improvement of FMD may lead to better the prognosis in patients with CAD (Brevetti et al 2003).

Positive_regulation (improvement) of FMD in brachial artery associated with coronary artery disease

1) Confidence 0.04 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464748 Disease Relevance 0.81 Pain Relevance 0

Interestingly, animal models of MCMV-induced SjS only require a single exposure to the virus which could serve as an ideal animal model examining the early phase of human SjS development.

Positive_regulation (induced) of SjS associated with syndrome and cytomegalovirus infection

2) Confidence 0.03 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3018660 Disease Relevance 1.39 Pain Relevance 0.10

General Comments

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