INT23923

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Context Info
Confidence 0.54
First Reported 1986
Last Reported 2010
Negated 1
Speculated 2
Reported most in Abstract
Documents 8
Total Number 10
Disease Relevance 2.46
Pain Relevance 2.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ltf) extracellular region (Ltf) molecular_function (Ltf)
cellular_component (Ltf) biological_process (Ltf) cytoplasm (Ltf)
Anatomy Link Frequency
phrenic 2
plasma 1
neurons 1
Ltf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 5 100.00 Very High Very High Very High
c fibre 4 100.00 Very High Very High Very High
Pain 2 100.00 Very High Very High Very High
Neuropathic pain 4 99.84 Very High Very High Very High
Hyperalgesia 2 99.84 Very High Very High Very High
allodynia 2 99.16 Very High Very High Very High
opioid receptor 2 98.52 Very High Very High Very High
Chronic pancreatitis 4 95.92 Very High Very High Very High
Dorsal horn neuron 1 93.72 High High
wide dynamic range 2 75.68 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 6 99.84 Very High Very High Very High
Hyperalgesia 2 99.84 Very High Very High Very High
Pancreatitis 5 99.52 Very High Very High Very High
Aids-related Complex 5 95.32 Very High Very High Very High
Hypoxia 13 88.04 High High
Paralysis 1 87.52 High High
Nociception 2 61.16 Quite High
Myocardial Infarction 2 54.88 Quite High
Cv General 3 Under Development 2 52.56 Quite High
Urological Neuroanatomy 2 50.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesized that the magnitude of hypoglossal and phrenic LTF would be differentially regulated by vagal afferent feedback in anesthetized and mechanically ventilated rats.
Regulation (regulated) of LTF in phrenic
1) Confidence 0.54 Published 2008 Journal Neurosci. Lett. Section Abstract Doc Link 18652877 Disease Relevance 0.15 Pain Relevance 0
However, the effects of vagotomy on LTF may not be so straight forward.
Regulation (effects) of LTF
2) Confidence 0.24 Published 2008 Journal Neurosci. Lett. Section Abstract Doc Link 18652877 Disease Relevance 0.14 Pain Relevance 0
The effects of vagotomy on LTF in rats are unknown.
Regulation (effects) of LTF
3) Confidence 0.24 Published 2008 Journal Neurosci. Lett. Section Abstract Doc Link 18652877 Disease Relevance 0.15 Pain Relevance 0
After a meal test in 88 patients suspected for pancreatitis no correlation between concentration of lactoferrin and amylase was found.
Regulation (concentration) of lactoferrin associated with pancreatitis
4) Confidence 0.23 Published 1986 Journal Scand. J. Gastroenterol. Suppl. Section Abstract Doc Link 2436285 Disease Relevance 0.36 Pain Relevance 0.34
In contrast, a stable LTF of C-fiber responses was obtained at 30 and 100 Hz CS, and at these frequencies there was a sharp increase in zif268 expression and appearance of Arc-positive neurons.
Regulation (responses) of LTF in neurons associated with c fibre and aids-related complex
5) Confidence 0.17 Published 2008 Journal Neuroscience Section Abstract Doc Link 18555615 Disease Relevance 0.48 Pain Relevance 0.69
The aim was to investigate the effect of propofol anesthesia on the phrenic long-term facilitation (pLTF) in rats.
Spec (investigate) Regulation (effect) of pLTF in phrenic associated with anesthesia
6) Confidence 0.15 Published 2010 Journal Respir Physiol Neurobiol Section Abstract Doc Link 20038457 Disease Relevance 0.37 Pain Relevance 0.19
Effect of prolonged administration of bovine lactoferrin in neuropathic pain: involvement of opioid receptors, nitric oxide and TNF-alpha.
Regulation (Effect) of lactoferrin associated with pain, neuropathic pain and opioid receptor
7) Confidence 0.14 Published 2010 Journal Life Sci. Section Title Doc Link 20045006 Disease Relevance 0.28 Pain Relevance 0.52
AIMS: This study aimed to investigate the effect of prolonged administration of bovine milk lactoferrin (bLF) on hyperalgesia and allodynia in a rat model of neuropathic pain and to determine the involvement of c-Fos, TNF-alpha, nitric oxide and opioidergic systems in this effect.
Spec (investigate) Regulation (effect) of lactoferrin associated with hyperalgesia, allodynia and neuropathic pain
8) Confidence 0.14 Published 2010 Journal Life Sci. Section Abstract Doc Link 20045006 Disease Relevance 0.37 Pain Relevance 0.41
In contrast, we observed no changes in plasma MPO and lactoferrin levels following stenting in patients with AMI.
Neg (no) Regulation (changes) of lactoferrin in plasma
9) Confidence 0.08 Published 2009 Journal Eur. J. Intern. Med. Section Body Doc Link 19712859 Disease Relevance 0.16 Pain Relevance 0
The present study assessed the effects of bovine milk-derived lactoferrin (bLf) on distress activities induced by maternal separation in 5- to 18-day-old rat pups.
Regulation (effects) of milk-derived lactoferrin
10) Confidence 0.03 Published 2003 Journal Brain Res. Section Abstract Doc Link 12850589 Disease Relevance 0 Pain Relevance 0.10

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